Clinical Policy Bulletin: Breath Tests of Airway Inflammation: Exhaled Nitric Oxide and Exhaled Breath Condensate pH
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ATS workshop proceedings: exhaled nitric oxide and nitric oxide oxidative metabolism in exhaled breath condensate.
The field of noninvasive assessment of airway inflammation has developed rapidly since the discoveries in the late 1980s that nitric oxide (NO) is a central biological mediator and, in 1991, that exhaled breath contained NO (1). Accompanying this was the realization that asthma is an inflammatory airway syndrome, best treated by antiinflammatory agents. Subsequently, exhaled NO was found to be ...
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weeks with noninvasive measures of airway inflammation including exhaled nitric oxide (eNO), sputum induction with bronchial hyperreactivity testing, and exhaled breath condensate. Physicians who were unaware of the results of inflammatory measures made reductions in the steroid dose on the basis of clinical assessment and spirometry. Multiple logistic-regression models were used to determine t...
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Description of Procedure or Service Current techniques for diagnosing and monitoring asthma and predicting exacerbations are suboptimal. Two new strategies, evaluation of exhaled nitric oxide and exhaled breath condensate are proposed. These techniques are also potentially useful in the management of other conditions such as chronic obstructive pulmonary disease (COPD) and chronic cough. There ...
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A irway inflammation plays a key role in asthma, chronic obstructive pulmonary disease (COPD) and other airway diseases. Noninvasive methods as tools to study these inflammatory processes and to monitor airway diseases are in high demand. This has lead to the rediscovery of sputum analysis and sputum induction as noninvasive tools to obtain samples from the airways [1]. Around this time increas...
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Bronchial asthma is one of the most prevalent respiratory conditions. Although it is defined as an inflammatory disease, the current guidelines for both diagnosis and follow-up of patients are based only on clinical and lung function parameters. Current research is focused on finding markers that can accurately predict future risk, and on assessing the ability of these markers to guide medical ...
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